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The results of this study suggest that MMJ may be a promising candidate for the treatment of epilepsy and its associated co-morbidities when used in conjunction with AEDs in MRE patients. This study suggests MMJ may improve overall quality of life, epilepsy, and co-morbidities associated with epilepsy. The high out-of-pocket costs and lack of insurance coverage associated with this treatment has been a major concern and deterring factor in patients participating in this study. Although this study lacks controls and is based on self-reporting, it serves as a pilot study for a larger study to quantify the effects of MMJ treatment on MRE and its co-morbidities.